Pittsburgh, February 19, 2008 — Avant Medical, a leading medical technology manufacturer based in San Diego, Calif., is currently developing the latest generation (dubbed Gen 3) of its Pulse Injection® technology for needle-free injection of medications. This innovative device, which will be capable of delivering up to 30 doses from a single medication reservoir, utilizes engineering resin and technical expertise from Bayer MaterialScience LLC (BMS).
Avant Medical’s patented products are intended for those who need to frequently self-administer medications or for use in a clinical setting by healthcare professionals. Pulse Injection uses vacuum stabilization and two-stage delivery to achieve reliable and comfortable injections. Each dose of medicine is delivered through a cassette with a nozzle component molded from BMS’ Makrolon® Rx2530 polycarbonate resin. The injector provides a fluid pathway for the drug, while also generating a pulse that punctures the skin.
A number of medical device manufacturers rely on Makrolon Rx2530 polycarbonate resin. It is used for medical device applications requiring minimum color change after exposure to sterilizing doses of gamma radiation. When standard grades of polycarbonate are exposed to gamma sterilization, the mechanical properties remain substantially unchanged, but there is a yellowing of the resin. Makrolon Rx2530 polycarbonate resin, however, contains proprietary gamma-sterilization technology that reduces initial yellowing.
Makrolon polycarbonate offers a combination of clarity, dimensional stability and ease of processing. The resin also meets the requirements of the FDA-modified ISO 10993, Part 1 “Biological Evaluation of Medical Devices” for 30-day indirect blood contact applications. These factors contributed to Avant Medical’s selection of BMS’ Makrolon Rx2530 polycarbonate for this application.
Also important was the need for the nozzle to withstand up to 45 impacts, thereby meeting the 50 percent design safety margin required by international standards. Molding optimization, which was guided by the technical support at BMS, played an important role in achieving the required strength, according to John Slate, Avant Medical vice president of operations.
“The technical staff at Bayer MaterialScience has been a great resource to call on,” said Slate. “They know so much about their materials and are willing to spend the time and effort to ensure we have success with our end product.”
“At BMS we have a combination of technical expertise and materials technology that has serviced the healthcare industry for over 40 years,” said Kevin Dunay, Market Segment Leader, Medical, BMS. “We are pleased that we were able to contribute on both these fronts to Avant Medical’s latest needleless injector – an innovative device that will benefit so many.”
Bayer MaterialScience LLC is one of the leading producers of polymers and high-performance plastics in North America and is part of the global Bayer MaterialScience business with nearly 14,900 employees at 30 sites around the world and 2006 sales of 10.2 billion euros from continuing operations. Our innovative developments in coatings, adhesive and sealant raw materials, polycarbonates, polyurethanes and thermoplastic urethane elastomers enhance the design and functionality of products in a wide variety of markets, including the automotive, construction, electrical and electronics, household and medical industries, and the sports and leisure fields. Our inorganic basic chemicals unit produces chlorine and related essential products for the chemicals industry. Let us give life to your vision. Bayer MaterialScience – Where VisionWorks.
Bayer Corporation, headquartered in Pittsburgh, is a subsidiary of Bayer AG, an international health care, nutrition and innovative materials group based in Leverkusen, Germany. In North America, Bayer had 2006 net sales of 7.8 billion euros and employed 17,200 at year end. Bayer’s three subgroups, Bayer HealthCare, Bayer CropScience and Bayer MaterialScience, improve people’s lives through a broad range of essential products that help prevent and treat diseases; protect crops and enhance yields; and advance automobile safety and durability.
Scott Hunsberger, Phone: 412-777-5200
For more information about BMS’ portfolio of engineering resins for the healthcare market, or other high performance Makrolon® based polycarbonate resins, call 1-800-662-2927, e-mail firstname.lastname@example.org or visit www.bayermaterialscienceNAFTA.com.